FIBER CONNECTIONS OF CORPUS STRIATUM AS SEEN IN MARCHI PREPARATIONS

Abstract

In this investigation isolated lesions have been made in various parts of the corpus striatum with the Horsley-Clarke apparatus and the resulting degenerations analyzed through the study of Marchi preparations. The results which have been obtained correct certain misapprehensions and clarify some ambiguities regarding the myelinated efferent fibers of the globus pallidus, and certain new details regarding them have been established. Aside from the very important work done by Wilson,¹this method has apparently not previously been used in the study of the corpus striatum. Most of the fiber connections in this region are too complicated to be followed in sections of normal brains stained by the Weigert method or other similar technics. Some studies have been made on human brains with long-standing lesions of the cortex, basal ganglia or tegmentum, in an attempt to determine, by the resulting atrophy of other parts, the connections which exist between the