Journal of Heterocyclic Chemistry · 1986 · 36 citations · 2 references
Natural SciencesChemistryMedicinal ChemistryDrug DiscoveryOrganic ChemistrySynthetic Medicinal ChemistryCross-coupling ReactionsHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsMacrocycle SynthesisOrganic SynthesisBioactive HeterocyclesBiological Activity FeaturesFused Heterocycle SynthesisNitrogen HeterocyclesPolycyclic HeterocyclesSubstituent Effects On Biological ActivityTriazole ChemistryTriazole Synthesis
Abstract The reaction of 3‐(2,4‐dichlorophenyl)‐5‐mercapto 1,2,4–1 H ‐triazole with α‐haloketones and with 1,2‐dibromoethane leading to the formation of fused heterocycles were carried out and the orientation of cyclization was studied. The reaction of 3‐(2,4‐dichlorophenyl)‐5‐mercapto‐4‐amino‐1,2,4‐s‐triazole with α‐haloketones
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