Journal of Magnetic Resonance Series B · 1994 · 186 citations · 0 references
EngineeringAnatomyPhysiologyBiological Transport PhenomenaBiomedical ImagingMedical PhysicsDiffusion ApproximationTransport In TissuesApparent Diffusion Coefficient AnalysisDiffusion BarriersDiffusion Coefficient DeterminationDiffusion Coefficient EstimationEffective Diffusivity In TissuesPassive DiffusionTime-dependent DiffusionTissue Diffusion
Interpretation of NMR diffusion data is complicated in the presence of diffusion barriers. In this study, restricted diffusion in cylinders is evaluated. A method is presented to determine the diameter of the cylinder and the unrestricted diffusion coefficient from the dependence of the trace of the diffusion tensor with diffusion time. This method is valid even if the orientation of the cylinders is unknown and varies within the sample. An example is given for the diffusion of phosphocreatine in the cylindrically shaped fibers of rabbit skeletal muscle.