Publication | Closed Access
Human AQP2 and MIP genes, two members of the MIP family, map within chromosome band 12q13 on the basis of two-color FISH
25
Citations
0
References
1995
Year
CytogeneticsGeneticsMip FamilyGenomic MechanismMolecular BiologyMolecular GeneticsGenomicsMip GenesGenetic VariationChromosomal RearrangementDuct Water ChannelBiologyDevelopmental BiologyGenetic DisorderNatural SciencesHuman Aqp2Genetic MechanismChromosome BiologyGene FamilyMedicine
The human AQP2 (collecting duct water channel, aquaporin 2) gene encodes a 271 amino acid protein and is a member of the MIP (major intrinsic protein of lens fiber) gene family. Using two-color fluorescence in situ hybridization on high-resolution R-banded chromosomes and human genomic DNA clones for AQP2 and MIP as probes, we found that both genes mapped closely within the human chromosome region 12q13.