Binding of typical and atypical antipsychotics to 5-HT1C and 5-HT2 sites: clozapine potently interacts with 5-HT1C sites

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

Herbert Y. Meltzer, Shin Matsubara, J C Lee · Journal of Pharmacology and Experimental Therapeutics · 1989 · 1.4K citations

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

Molecular Pharmacology, Molecular Neuroscience, Neurophysiology +12

Serotonergic component of neuroleptic receptors

Josée E. Leysen, C. J. E. Niemegeers, J.P. Tollenaere et al. · Nature · 1978 · 626 citations

Neurophysiology, Physiology, Neurotransmitter +8

The binding of serotonergic ligands to the porcine choroid plexus: Characterization of a new type of serotonin recognition site

Ángel Pazos, Daniël Hoyer, José Palacios · European Journal of Pharmacology · 1984 · 598 citations

Biochemistry, Serotonin Recognition Site, Serotonergic Ligands +11

Effect of typical and atypical antipsychotic drugs on 5-HT2 receptor density in rat cerebral cortex

Shigehiro Matsubara, Herbert Y. Meltzer · Life Sciences · 1989 · 90 citations

Neuropsychology, Atypical Antipsychotic Drugs, Psychiatry +14