Binding of typical and atypical antipsychotics to 5-HT1C and 5-HT2 sites: clozapine potently interacts with 5-HT1C sites

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

Herbert Y. Meltzer, Shin Matsubara, J C Lee · Journal of Pharmacology and Experimental Therapeutics · 1989 · 1.4K citations

Medicine, Pharmacology, Psychiatry +17

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

Medicine, Medicinal Chemistry, Pharmacology +17

Serotonergic component of neuroleptic receptors

Josée E. Leysen, C. J. E. Niemegeers, J.P. Tollenaere et al. · Nature · 1978 · 626 citations

Life Sciences, Neuroscience, Pharmacology +14

The binding of serotonergic ligands to the porcine choroid plexus: Characterization of a new type of serotonin recognition site

Ángel Pazos, Daniël Hoyer, José Palacios · European Journal of Pharmacology · 1984 · 598 citations

Life Sciences, Neuroscience, Pharmacology +17

Effect of typical and atypical antipsychotic drugs on 5-HT2 receptor density in rat cerebral cortex

Shigehiro Matsubara, Herbert Y. Meltzer · Life Sciences · 1989 · 90 citations

Medicine, Neuroscience, Pharmacology +15