Catalytic Oxidation of C(<i>sp</i>³)H Bonds Induced by a Radical Cation Salt: Construction of 1,4‐Dihydropyridines Using a Fragment‐Reassembly Strategy

Abstract

Abstract A fragment‐reassembly strategy was applied to the construction of 1,4‐dihydropyridines and phosphorus‐substituted 1,4‐dihydropyridines under catalytic radical cation salt‐induced C( sp ) 3 H functionalization of glycine derivatives. Mechanistic studies show that domino C(sp) 3 H bond oxidation and CN bond cleavage reactions are involved. magnified image