American Journal of Public Health · 1990 · 54 citations · 13 references
Public HealthChild HealthMaternal HealthEnvironmental HealthInfant HealthPediatric EpidemiologyMaternal SmokingNeonatal EpidemiologyRespiratory Disease Epidemiology In ChildrenTobacco EpidemiologyTobacco UseCotinine Exposure AssessmentEnvironmental Tobacco SmokeEnvironmental Tobacco Smoke ExposureMaternal Cigarette SmokingMaternal Smoking ExposureTobacco Smoke ExposureTobacco SmokingUrine Sample Collection
We collected information about household smoking habits from 518 mothers when they made their first well child visit with a 6 to 8-week old infant. A urine sample was also collected from the infant, the cotinine concentration measured, and the measurement correlated with data provided by the mother. Eight percent of the infant urine cotinine values fell at or above 10 micrograms/L in the 305 households where no smoking was reported. Corresponding rates were 44 percent in the 96 households where a member other than the mother smoked, 91 percent in the 43 households where only the mother smoked, and 96 percent in the 74 households where both the mother and another household member smoked. In households where the mother smoked, infant urine cotinine levels were lower in the summer, and higher when the infant was breast-fed. A screening question about family smoking habits in conjunction with well child care could effectively define a group of infants exposed to environmental tobacco smoke and thus be at greater risk for respiratory diseases.
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Cotinine disposition and effects
Neal L. Benowitz, Florence Kuyt, Peyton Jacob et al. · Clinical Pharmacology & Therapeutics · 1983 · 490 citations
Pharmacy, Clinical Pharmacokinetics, Noncompartmental Analysis +12
Measuring the Exposure of Infants to Tobacco Smoke
Robert A. Greenberg, Nancy J. Haley, Ruth A. Etzel et al. · New England Journal of Medicine · 1984 · 233 citations