RSPO4 Is the Major Gene in Autosomal-Recessive Anonychia and Mutations Cluster in the Furin-Like Cysteine-Rich Domains of the Wnt Signaling Ligand R-spondin 4

R-Spondin2 Is a Secreted Activator of Wnt/β-Catenin Signaling and Is Required for Xenopus Myogenesis

Olga Kazanskaya, Andrei Glinka, Iván del Barco Barrantes et al. · Developmental Cell · 2004 · 431 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +15

A general method for the detection of large CAG repeat expansions by fluorescent PCR.

Jon Warner, L H Barron, David Goudie et al. · Journal of Medical Genetics · 1996 · 294 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Mouse Cristin/R-spondin Family Proteins Are Novel Ligands for the Frizzled 8 and LRP6 Receptors and Activate β-Catenin-dependent Gene Expression

Ju‐Suk Nam, Taryn J. Turcotte, Peter F. Smith et al. · Journal of Biological Chemistry · 2006 · 283 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

R-Spondin Proteins: A Novel Link to β-catenin Activation

Kyung‐Ah Kim, Jingsong Zhao, Susan Andarmani et al. · Cell Cycle · 2005 · 252 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia

Diana C. Blaydon, Yoshiyuki Ishii, Edel A. O’Toole et al. · Nature Genetics · 2006 · 192 citations

Life Sciences, Genetics, Molecular Genetics +11