Concepedia

Publication | Open Access

NADPH Oxidase 4 Induces Cardiac Fibrosis and Hypertrophy Through Activating Akt/mTOR and NFκB Signaling Pathways

DOIFull Paper Access

238

Citations

41

References

2015

Year

Qingwei Zhao, Suryavathi Viswanadhapalli, Paul J. Williams, Qian Shi, Chunyan Tan, Xiaolan Yi, Hanna E. Abboud
Circulation

Abstract

Upregulation of Nox4 in the myocardium causes cardiac remodeling through activating Akt-mTOR and NFκB signaling pathways. Inhibition of Nox4 has therapeutic potential to treat cardiac remodeling.

References

YearCitations

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