2,3,6,7‐Tetrasubstituted Perhydroanthracenes: Stereoselective Synthesis and Biconformationality Studies

Abstract

2,3,6,7-Tetrasubstituted perhydroanthracenes with the relative configuration 2β,3α,4aα,6β,7α,8aβ,9aα,10aβ have been synthesized stereoselectively. The biconformationality of these compounds has been investigated in solution by NMR and in the solid state by X-ray crystallography. A triple-ring flip 2 → 3 was realized for the first time by the covalently induced transition 29 → 30.