The time-course of the induction of reparative dentine formation in monkeys by recombinant human osteogenic protein-1

Recombinant human bone morphogenetic protein induces bone formation.

Elizabeth A. Wang, Vicki Rosen, Josephine D’Alessandro et al. · Proceedings of the National Academy of Sciences · 1990 · 1.5K citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +13

Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development

Seppo Vainio, Irina Karavanova, Adrian K. Jowett et al. · Cell · 1993 · 906 citations

Dentistry, Craniofacial Biology, Oral Biology +13

Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro.

T. Kuber Sampath, James C. Maliakal, Peter V. Hauschka et al. · Journal of Biological Chemistry · 1992 · 680 citations · Full text

Medicine, Cell Biology, Molecular Biology +17

Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for <i>Bone Morphogenetic Protein-2A (BMP-2A)</i>

Karen M. Lyons, Ron W. Pelton, Brigid L.M. Hogan · Development · 1990 · 616 citations

Life Sciences, Craniofacial Biology, Developmental Biology +17

Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth factor-beta superfamily.

T. Kuber Sampath, John E. Coughlin, Ricci Whetstone et al. · Journal of Biological Chemistry · 1990 · 372 citations · Full text

Medicine, Biochemistry, Molecular Biology +17