Journal of Clinical Investigation · 1962 · 116 citations · 18 references
Life SciencesBiochemistryEndocrinologyChromatographic AnalysisEndocrine Nuclear MedicineHormone BiochemistryChromatographyHormone MetabolismThyroid EndocrinologyThyroid Hormone BiochemistrySerum Thyroid-stimulating Hormone MeasurementThyroid Function EvaluationThyroid Function TestingThyroid Function TestsThyroid-stimulating Hormone Testing
In the present investigation the existence of "free" thyroxine in human serum was repeatedly verified by dialysis through cellophane, with paper chromatographic identification of thyroxine in the dialysate. Methods were developed for measurement of the minute amount of thyroxine present in the dialysate that was considered to represent the unbound or diffusible fraction of the hormone in serum.
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Proteins Associated with the Thyroid Hormones
Jacob Robbins, J. E. RALL · Physiological Reviews · 1960 · 355 citations
The interaction of thyroid hormones and protein in biological fluids.
Regulation of the peripheral metabolism of the thyroid hormones.
Ingbar Sh, Norbert Freinkel · PubMed · 1960 · 136 citations