Angewandte Chemie International Edition · 1998 · 119 citations · 0 references
Natural SciencesBiochemistryChemistryBiocatalysisEnzymologyInorganic ChemistryBioinorganic ChemistryCalixarene ChemistryCoordination ChemistryLigand BindingMetal-ligand BondingTransition Metal ComplexesCatalytic CalixarenesEnzymesLigand Effects On ReactivityMetal Coordination
A cavity that acts as a molecular funnel is formed from calix[6]arene 1 and [CuI(NCCH3)4]PF6 [Eq. (a)]. An exchange of the well-protected acetonitrile ligand for other nitriles RCN is only possible with small R groups. The protection of the copper ions precludes oxidative dimerization; thus, the complexes mimic the mononuclear site of copper enzymes.