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Calixarene-Based Copper(I) Complexes as Models for Monocopper Sites in Enzymes

DOI

119

Citations

0

References

1998

Year

Sébastien Blanchard, Loı̈c Le Clainche, Marie‐Noëlle Rager, B. Chansou, Jean‐Pierre Tuchagues, Arthur F. Duprat, Yves Le Mest, Olivia Reinaud
Angewandte Chemie International Edition

Abstract

A cavity that acts as a molecular funnel is formed from calix[6]arene 1 and [Cu<sup>I</sup> (NCCH<sub>3</sub> )<sub>4</sub> ]PF<sub>6</sub> [Eq. (a)]. An exchange of the well-protected acetonitrile ligand for other nitriles RCN is only possible with small R groups. The protection of the copper ions precludes oxidative dimerization; thus, the complexes mimic the mononuclear site of copper enzymes.