Concepedia

Low-Grade Systemic Inflammation Causes Endothelial Dysfunction in Patients with Hashimoto’s Thyroiditis

Stefano Taddei, Nadia Caraccio, Agostino Virdis, Angela Dardano, Daniele Versari, Lorenzo Ghiadoni, Ele Ferrannini, Antonio Salvetti, Fabio Monzani

The Journal of Clinical Endocrinology & Metabolism · 2006 · 186 citations · 31 references

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Abstract

In sHT patients, low-grade chronic inflammation causes endothelial dysfunction and impaired nitric oxide availability by a COX-2-dependent pathway leading to increased production of oxidative stress.

References

31

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Richard Palmer, Anthony G. Ferrige, Salvador Moncada · Nature · 1987 · 10.7K citations

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The Colorado Thyroid Disease Prevalence Study

Gay J. Canaris, Neil Manowitz, Gilbert H. Mayor et al. · Archives of Internal Medicine · 2000 · 2.8K citations

Prognostic Impact of Coronary Vasodilator Dysfunction on Adverse Long-Term Outcome of Coronary Heart Disease

Volker Schächinger, Martina Britten, Andreas M. Zeiher · Circulation · 2000 · 2.6K citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

David S. Bredt, Paul M. Hwang, Charles E. Glatt et al. · Nature · 1991 · 2.4K citations

, , +6

Long-Term Follow-Up of Patients With Mild Coronary Artery Disease and Endothelial Dysfunction

Jassim Al Suwaidi, Shuichi Hamasaki, Stuart T. Higano et al. · Circulation · 2000 · 2K citations · Full text