American Journal of Medical Genetics · 1979 · 27 citations · 11 references
Life SciencesGeneticsHuman GeneticsMedical GeneticsQuantitative GeneticsCongenital DisordersDominance EffectsHeritabilityTwin StudiesDominance Genetic VarianceDominance HeritabilityDominance HypothesisDominance VarianceFamily-based HeritabilityMultifactorial Inheritance ModelsSex Differences In Twin HeritabilityTwin Study Heritability
In fathers and mothers of 707 index patients with operated indirect congenital inguinal hernia (CIH) born in Budapest during the years 1962-1966 the frequency of CIH was two and five to six times higher, respectively, than in the general population. The rate of affected sibs was higher than that of parents but was greatly dependent on the sex of the index patient. Heritability estimates of CIH vary significantly in parents (0.35 +/- 0.12) and in sibs (0.78 +/- 0.14). In twins the heritability is 0.77. These data agree with the multifactorial threshold model involving dominance variance.
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C. O. Carter · 1969 · 296 citations
On the origin and nature of hernia
Arthur Keith · British journal of surgery · 1924 · 152 citations
A. G. Marshall, E. O. Hutchinson, J. Honisett · BMJ · 1962 · 37 citations · Full text
Genetic study of indirect inguinal hernia.
Yaoqin Gong, Changshun Shao, Qiao Sun et al. · Journal of Medical Genetics · 1994 · 33 citations · Full text