Concepedia

A simulation-based comparison of the traditional method, Rolling-6 design and a frequentist version of the continual reassessment method with special attention to trial duration in pediatric Phase I oncology trials

Arzu Onar‐Thomas, Zang Xiong

Contemporary Clinical Trials · 2010 · 45 citations · 16 references

DOI

Concepts

References

16

Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer

John O’Quigley, Margaret S. Pepe, Lloyd D. Fisher · Biometrics · 1990 · 1.6K citations

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Some practical improvements in the continual reassessment method for phase I studies

Steven N. Goodman, Marianna Zahurak, Steven Piantadosi · Statistics in Medicine · 1995 · 474 citations

, , +19

A comparison of two phase I trial designs

Edward L. Korn, Douglas Midthune, T. Timothy Chen et al. · Statistics in Medicine · 1994 · 299 citations

Shortening the Timeline of Pediatric Phase I Trials: The Rolling Six Design

Jeffrey Skolnik, Jeffrey S. Barrett, Bhuvana Jayaraman et al. · Journal of Clinical Oncology · 2008 · 261 citations · Full text

Phase I trial of imatinib in children with newly diagnosed brainstem and recurrent malignant gliomas: A Pediatric Brain Tumor Consortium report1

Ian F. Pollack, Regina I. Jakacki, Susan M. Blaney et al. · Neuro-Oncology · 2007 · 188 citations · Full text

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