Additive effect of drospirenone/17-β-estradiol in hypertensive postmenopausal women receiving enalapril1

Richard A. Preston, A ALONSO, D PANZITTA, Ping Zhang, Adel H. Karara

American Journal of Hypertension · 2002 · 53 citations · 25 references

DOIFull text

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Abstract

Our results suggest a significant additive BP-lowering effect of DRSP/E2 on both systolic and diastolic BP in hypertensive postmenopausal women receiving ENA, consistent with an antimineralocorticoid effect. DRSP/E2, a HRT with antimineralocorticoid effects, could offer a novel potential mechanism for reducing cardiovascular end points in postmenopausal women.

References

25