Concepedia

Possible Pathophysiological Roles of Mitogen‐Activated Protein Kinases (MAPKs) in Endometriosis

Osamu Yoshino, Yutaka Osuga, Yasushi Hirota, Kaori Koga, Tetsuya Hirata, Miyuki Harada, Chieko Morimoto, Tetsu Yano, Osamu Nishii, Osamu Tsutsumi,

American Journal of Reproductive Immunology · 2004 · 132 citations · 23 references

DOI

Abstract

Given the current theory that inflammatory changes are involved in the progression of endometriosis, MAPKs could play as pivotal intracellular signal transducers in endometriotic cells, and thus have a pathophysiological role in the disease.

References

23

Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions

Endocrine Reviews · 2001 · 1.1K citations

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Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosis

H. Ota, S. Igarashi, Mamoru Sasaki et al. · Human Reproduction · 2001 · 296 citations

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Interleukin-6 secretion in vitro is up-regulated in ectopic and eutopic endometrial stromal cells from women with endometriosis.

Jennifer F. Tseng, I. Ryan, Terry D. Milam et al. · The Journal of Clinical Endocrinology & Metabolism · 1996 · 279 citations · Full text

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Isolation, characterization, and comparison of human endometrial and endometriosis cells in vitro.

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Pathogenetic Significance of Increased Levels of Interleukin-8 in the Peritoneal Fluid of Patients with Endometriosis

Tomio Iwabe, Tasuku Harada, Toshiyuki Tsudo et al. · Fertility and Sterility · 1998 · 191 citations · Full text

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