New rapid bed‐side test to predict preterm delivery: phosphorylated insulin‐like growth factor binding protein‐1 in cervical secretions

Abstract

The presence of cervical phIGFBP-1 is predictive of preterm delivery < 37 weeks of gestation. Our study shows that cervical detection of phIGFBP-1 by immunochromotography is a rapid and easily applicable test that highly anticipates preterm delivery in patients at risk.

References

Page 1

	Year	Citations
Insulin-Like Growth Factor-Binding Proteins in Serum and Other Biological Fluids: Regulation and Functions Sujatha Rajaram Endocrine Reviews Growth HormoneOther Biological FluidsBiochemistryMedicineNatural Sciences	1997	402
The preterm prediction study: Fetal fibronectin testing and spontaneous preterm birth R GOLDENBERG, B Mercer, Paul Meis, Obstetrics and Gynecology	1996	289
Primary structure of human insulin‐like growth factor‐binding protein/placental protein 12 and tissue‐specific expression of its mRNA Mervi Julkunen, Riitta Koistinen, Katriina Aalto‐Setälä, FEBS Letters	1988	212
Radioimmunoassay of placental protein 12: Levels in amniotic fluid, cord blood, and serum of healthy adults, pregnant women, and patients with trophoblastic disease Eeva‐Marja Rutanen, H. Bohn, Markku Seppälä American Journal of Obstetrics and Gynecology Maternal ImmunizationAmniotic FluidImmunologyGynecologyPathology	1982	167
Multicenter randomized, controlled trial of a preterm birth prevention program American Journal of Obstetrics and Gynecology Pregnancy PreventionPreterm LaborReproductive HealthPediatricsGynecology	1993	113
Evaluation of a rapid strip test for insulin-like growth factor binding protein-1 in the diagnosis of ruptured fetal membranes Eeva‐Marja Rutanen, Tytti Kärkkäinen, Johanna Lehtovirta, Clinica Chimica Acta Developmental BiologyGrowth HormoneInsulin-like Growth FactorHuman GrowthMedicine	1996	99
Gestational Age-Dependent Expression of Insulin-Like Growth Factor-Binding Protein-1 (IGFBP-1) Phosphoisoforms in Human Extraembryonic Cavities, Maternal Serum, and Decidua Suggests Decidua as the Primary Source of IGFBP-1 in these Fluids during Early Pregnancy1 N Martina, E. Kim, Usha Chitkara, The Journal of Clinical Endocrinology & Metabolism	1997	92
Prospective evaluation of a risk scoring system for predicting preterm delivery in black inner city women. Denise M. Main, Douglas K. Richardson, Steven G. Gabbe, PubMed Score CutoffReproductive HealthGynecologyPreterm Birth PredictionSocial Determinants Of Health	1987	84
Insulin‐like growth factor‐binding protein‐1 in cervical secretion as a predictor of preterm delivery M Kekki, Tapio Kurki, Tytti Kärkkäinen, Acta Obstetricia Et Gynecologica Scandinavica	2001	77
Phosphorylated isoforms of insulin-like growth factor binding protein-1 in the cervix as a predictor of cervical ripeness Mika Nuutila Obstetrics and Gynecology	1999	61

Page 1