Synlett · 2009 · 109 citations · 0 references
5-Substituted 1H-tetrazolesChemical EngineeringDiversity Oriented SynthesisEngineeringOrganic ChemistryOrganic NitrilesAdvantageous SynthesisCatalysisChemistrySynthesis MethodSynthetic Chemistry
An advantageous synthesis of 5-substituted 1H-tetrazoles has been developed by treatment of organic nitriles with NaN3 in the presence of iodine or the heterogeneous catalyst, silica-supported sodium hydrogen sulfate (NaHSO4˙SiO2).