Concepedia

The expression of P‐glycoprotein is increased in vessels with blood‐brain barrier impairment in a stroke‐prone hypertensive model

M Ueno, Toshitaka Nakagawa, Chih‐Ling Huang, M. Ueki, Takashi Kusaka, Naohisa Hosomi, Kenji Kanenishi, M. Onodera, Bin Wu, H. Sakamoto

Neuropathology and Applied Neurobiology · 2008 · 28 citations · 29 references

DOI

Abstract

These findings indicate that the expression of P-glycoprotein is increased in BBB-damaged hippocampal vessels in hypertensive SHRSP compared with those in WKY rats.

References

29

Development of a Strain of Spontaneously Hypertensive Rats

Kôzô Okamoto, Kyuzo Aoki · Japanese Circulation Journal · 1963 · 2.5K citations

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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

Alfred H. Schinkel, Johan W. Jonker · Advanced Drug Delivery Reviews · 2003 · 1.4K citations

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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

Alfred H. Schinkel, Johan W. Jonker · Advanced Drug Delivery Reviews · 2012 · 1.2K citations

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P-Glycoprotein, a gatekeeper in the blood–brain barrier

Alfred H. Schinkel · Advanced Drug Delivery Reviews · 1999 · 949 citations

, , +6

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

Marcel Kool, Marcel de Haas, George L. Scheffer et al. · PubMed · 1997 · 898 citations

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