The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3

Receptor Specificity of the Fibroblast Growth Factor Family

David M. Ornitz, Jennifer S. Colvin, Donald G. McEwen et al. · Journal of Biological Chemistry · 1996 · 1.9K citations · Full text

Fibrosis, Signal Transduction, Developmental Biology +15

Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndrome

Andrew O.M. Wilkie, Sarah F. Slaney, Michael Oldridge et al. · Nature Genetics · 1995 · 925 citations

Mendelian Disorder, Autoimmune Disease, Genetic Disorder +9

SH2-Containing Phosphotyrosine Phosphatase as a Target of Protein-Tyrosine Kinases

Gen‐Sheng Feng, Chi-Chung Hui, Tony Pawson · Science · 1993 · 669 citations

Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3

Marta Chesi, Elena Nardini, Leslie A. Brents et al. · Nature Genetics · 1997 · 646 citations · Full text

Hematological Malignancy, Frequent Translocation T, Immunology +8

Structural Basis for FGF Receptor Dimerization and Activation

A.N. Plotnikov, Joseph Schlessinger, Stevan R. Hubbard et al. · Cell · 1999 · 606 citations · Full text