Concepedia

Functional KCa3.1 K+ channels are required for human lung mast cell migration

Glenn Cruse

Thorax · 2006 · 129 citations · 35 references

DOIFull text

Open access

Abstract

Since modulation of K(Ca)3.1 can inhibit HLMC chemotaxis to diverse chemoattractants, the use of K(Ca)3.1 blockers such as TRAM-34 could provide new therapeutic strategies for mast cell mediated diseases such as asthma.

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