Zur Reaktivität von C=N-Doppelbindungssystemen, X Synthesen von kondensierten Heterocyclen. / The Reactivity of C=N-Double Bond Systems, Χ Synthesis of Condensed Heterocycles - Concepedia

Concepedia

Publication | Open Access

Zur Reaktivität von C=N-Doppelbindungssystemen, X Synthesen von kondensierten Heterocyclen. / The Reactivity of C=N-Double Bond Systems, Χ Synthesis of Condensed Heterocycles

DOI Full Paper Access

26

Citations

0

References

1976

Year

Otto S. Wolfbeis, Erich Ziegler

Zeitschrift für Naturforschung B

EngineeringHeterocyclicCyclohexanedione-1,3 Yields Anilinomethylene-cyclohexanedione-1,3Condensed Heterocyclesχ SynthesisOrganic ChemistryC=n-double Bond SystemsChemistryHeterocycle ChemistryPharmacologySynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringCombined Action

Abstract

The combined action of orthoformate and aniline upon cyclohexanedione-1,3 yields anilinomethylene-cyclohexanedione-1,3, which react with cyanoacetate or malodinitrile in DMF in the presence of KOH to give ethyl-1-phenyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylates (or -carbonitrils)