Concepedia

IκB Genetic Polymorphisms and Invasive Pneumococcal Disease

S. Jonathan Chapman, Chiea Chuen Khor, Fredrik Vannberg, A J Frodsham, Andrew J. Walley, Christopher W.H. Davies, Shelley Segal, Catrin E. Moore, Stephen H. Gillespie, Paul Denny,

American Journal of Respiratory and Critical Care Medicine · 2007 · 84 citations · 35 references

DOI

Abstract

NFKBIA polymorphisms associate with susceptibility to IPD. Genetic variation in an inhibitor of NF-kappaB therefore not only causes a very rare immunodeficiency state but may also influence the development of common infectious disease.

References

35

Haploview: analysis and visualization of LD and haplotype maps

Jeffrey C. Barrett, Ben Fry, Julian Maller et al. · Bioinformatics · 2004 · 14.5K citations · Full text

The Structure of Haplotype Blocks in the Human Genome

Stacey Gabriel, S. F. Schaffner, Huy Nguyen et al. · Science · 2002 · 5.8K citations

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The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation

Alexander Hoffmann, Andre Levchenko, Martin Scott et al. · Science · 2002 · 1.9K citations

Cutting Edge: Recognition of Gram-Positive Bacterial Cell Wall Components by the Innate Immune System Occurs Via Toll-Like Receptor 2

Atsutoshi Yoshimura, Egil Lien, Robin R. Ingalls et al. · The Journal of Immunology · 1999 · 1.2K citations · Full text

Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression

David E. Nelson, Adaoha Ihekwaba, Malcolm C. Elliott et al. · Science · 2004 · 1.2K citations