Enhanced Expression of Interleukin-8 and Activation of Nuclear Factor Kappa-B in Endoscopy-negative Gastroesophageal Reflux Disease

Hajime Isomoto, Vladimir Saenko, Yusei Kanazawa, Yoshito Nishi, Akira Ohtsuru, Kenichiro Inoue, Yuko Akazawa, Fuminao Takeshima, Katsuhisa Omagari, Masanobu Miyazaki,

The American Journal of Gastroenterology · 2004 · 84 citations · 34 references

Abstract

Our results demonstrate enhanced mucosal expression of IL-8 in incipient GERD even without mucosal breaks. NF-kappaB activation may be implicated in the pathogenesis in GERD.

References

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