TEMPERATURE RESPONSES TO MONOAMINES AND AN INHIBITOR OF MAO INJECTED INTO THE CEREBRAL VENTRICLES OF RATS

Abstract

The effects on body temperature of noradrenaline, adrenaline and 5-hydroxytryptamine (5-HT), when injected into the cerebral ventricles vary in different species. For instance, the two catecholamines lower body temperature in cats, dogs and monkeys, raise it in rabbits and sheep, and have no effect on goats and oxen. On the other hand, 5-HT raises temperature in cats, dogs and monkeys, has a weak and inconsistent hypothermic effect in rabbits and sheep, and produces pronounced hypothermia in goats and oxen (von