Concepedia

Disease Course of Patients with X-linked Retinitis Pigmentosa due to<i>RPGR</i>Gene Mutations

Michael A. Sandberg, Bernard Rosner, Carol Weigel-DiFranco, Thaddeus P. Dryja, Eliot L. Berson

Investigative Ophthalmology & Visual Science · 2007 · 155 citations · 18 references

DOI

Abstract

Patients with X-linked retinitis pigmentosa due to RPGR mutations lose visual acuity and visual field more rapidly than do patients with dominant retinitis pigmentosa due to RHO mutations.

References

18

A gene (RPGR) with homology to the RCC1 guanine nucleotide exchange factor is mutated in X–linked retinitis pigmentosa (RP3)

A Meindl, Katherine L. Dry, Karin A. Herrmann et al. · Nature Genetics · 1996 · 479 citations

, , +11

Mutational hot spot within a new RPGR exon in X-linked retinitis pigmentosa

R. Vervoort, Alan Lennon, Alan C. Bird et al. · Nature Genetics · 2000 · 437 citations

, , +9

Natural Course of Retinitis Pigmentosa Over a Three-Year Interval

Eliot L. Berson, Michael A. Sandberg, Bernard Rosner et al. · American Journal of Ophthalmology · 1985 · 316 citations

, ,

A one-hit model of cell death in inherited neuronal degenerations

Geoff Clarke, Richard A. Collins, Blair R. Leavitt et al. · Nature · 2000 · 310 citations

, , +10

Non-linear projection of the retinal image in a wide-angle schematic eye.

N. Drasdo, C FOWLER · British Journal of Ophthalmology · 1974 · 298 citations · Full text