Rapid isolation of antigen-specific antibody-secreting cells using a chip-based immunospot array

Continuous cultures of fused cells secreting antibody of predefined specificity

Georges Köhler, César Milstein · Nature · 1975 · 17.1K citations

Immunocytochemical Technique, Cell Division, Immunology +8

Phage antibodies: filamentous phage displaying antibody variable domains

John McCafferty, Andrew D. Griffiths, Greg Winter et al. · Nature · 1990 · 2.4K citations

Phage Biology, Immunology, Antibody Engineering +4

Maintenance of Serological Memory by Polyclonal Activation of Human Memory B Cells

Nadia L. Bernasconi, Elisabetta Traggiai, Antonio Lanzavecchia · Science · 2002 · 1.3K citations

Human Memory B, Humoral Response, Immunology +22

A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells

Cécil Czerkinsky, Lars‐Åke Nilsson, Håkan Nygren et al. · Journal of Immunological Methods · 1983 · 1.1K citations

Specific Antibody-secreting Cells, Autoimmune Disease, Medicine +11

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

Jens Wrammert, Kenneth G. C. Smith, Joe Miller et al. · Nature · 2008 · 1K citations · Full text

Medicine, Immunology, Virology +4