Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity

References

Page 1

	Year	Citations
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene Dennis J. Slamon, Gary M. Clark, Steven Wong, Science	1987	11.6K
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor Anne Brunet, Azad Bonni, Michael J. Zigmond, Cell Systems BiologySignal TransductionCell RegulationForkhead Transcription FactorSignaling Pathway	1999	6.5K
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B Darren A.E. Cross, Dario R. Alessi, Philip Cohen, Nature Signal TransductionMolecular PhysiologyBiochemistryInsulin ManagementDiabetes	1995	5.2K
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Manfred Gossen, Heidelberg Bujard Proceedings of the National Academy of Sciences Viral ReplicationMolecular RegulationImmunologyMolecular BiologyEscherichia Coli	1992	4.9K
Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy Marco Sandri, Claudia Sandri, Alex Gilbert, Cell Transcriptional RegulationSkeletal MuscleGeneticsMolecular GeneticsGene Expression	2004	2.9K
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress Geert J.P.L. Kops, Tobias B. Dansen, Paulien E. Polderman, Nature Reductive StressTranscriptional RegulationSystems BiologyCell RegulationRedox Regulator	2002	1.5K
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1 René H. Medema, Geert J.P.L. Kops, Johannes L. Bos, Nature Transcriptional RegulationSystems BiologySignal TransductionSignaling PathwayCell Division	2000	1.4K
Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells Binhua P. Zhou, Yong Liao, Weiya Xia, Nature Cell Biology Signal TransductionSignaling PathwayCell RegulationMedicineNatural Sciences	2001	1.1K
Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta. Inga Reynisdóttir, Kornélia Polyák, Antonio Iavarone, Genes & Development CytokineSignal TransductionG1 ProgressionCell DivisionSignaling Pathway	1995	963
HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation Binhua P. Zhou, Yong Liao, Weiya Xia, Nature Cell Biology Cell RegulationMedicineHer-2/neu InducesTumor SuppressorCancer Biology	2001	937

Page 1