Concepedia

Traditional biomarkers in narcolepsy: experience of a Brazilian sleep centre

Fernando Morgadinho Santos Coelho, Márcia Pradella-Hallinan, Mário Pedrazzoli, Carlos Augusto Senne Soares, Gustavo Bruniera Peres Fernandes, André Leite Gonçalves, Sérgio Tufik, Lia Bittencourt

Arquivos de Neuro-Psiquiatria · 2010 · 10 citations · 12 references

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Abstract

This results were comparable with other authors, confirming the utility of using specific biomarkers (HLA-DQB1*0602 allele and Hypocretin-1 CSF level) in narcolepsy with cataplexy. However, the HLADQB1*0602 allele and Hypocretin-1 level are insufficient to diagnose of narcolepsy without cataplexy.

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