Organometallics · 2001 · 126 citations · 10 references
Natural SciencesChemical EngineeringChemistryCatalysisInorganic ChemistryOrganic ChemistryAcid-base CatalysisCatalyst PreparationCatalytic MechanismsIndustrial CatalysisOrganic SynthesisAlkylation ReactionsHydroboration Of AlkynesTriple Bonds
Hydroaminations of carbon−carbon triple bonds with primary amines are catalyzed with commercially available Ti(NMe 2 ) 4 . The reaction is surprisingly fast with many substrates and often selective for the Markovnikov product with terminal alkynes. The scope of the catalysis was investigated with a variety of amines and alkynes; arylamines and 1-hexyne were found to be especially good substrates.
10