The Relationship Between Peripheral Levels of Leukocytes and Neutrophils and Periodontal Disease Status in a Patient With Congenital Neutropenia

Abstract

This report demonstrates for the first time that periodontal therapy, resulting in decreased bacterial load, may result in restoration of normal levels of circulating neutrophils in individuals with congenital neutropenia under treatment with rhG-CSF. The results also suggest that periodontal pathogens may be associated with depressed neutrophil levels, even when patients receive treatment for neutropenia.