Thyrocalcitonin. II. Struktur von α‐Thyrocalcitonin

Abstract

Abstract The highly active peptide hormones isolated from pig thyroids – i.e. α‐thyrocalcitonin and its sulfoxide, containing 32 amino acid residues – were subjected to sequence studies using chemical and enzymatic methods. On the basis of these studies the following structure was derived for α‐thyrocalcitonin: magnified image In the α‐thyrocalcitonin sulfoxide (designated formerly as β‐thyrocalcitonin) the methionine residue is replaced by methionine sulfoxide.