Leukotriene-dependent airway anaphylaxis in guinea pigs

Allergen challenge of lung tissue from asthmatics elicits bronchial contraction that correlates with the release of leukotrienes C4, D4, and E4.

Sven‐Erik Dahlén, Göran K. Hansson, Per Hedqvist et al. · Proceedings of the National Academy of Sciences · 1983 · 421 citations · Full text

Life Sciences, Immunology, Pharmacology +15

Prostaglandin endoperoxides VII. Novel transformations of arachidonic acid in guinea pig lung

Mats Hámberg, Bengt Samuelsson · Biochemical and Biophysical Research Communications · 1974 · 228 citations

Life Sciences, Biochemistry, Pharmacology +14

6,9-deepoxy-6,9,-(phenylimino)-delta 6,8-prostaglandin I1, (U-60,257), a new inhibitor of leukotriene C and D synthesis: in vitro studies.

Bach Mk, Brashler, Smith Hw et al. · PubMed · 1982 · 71 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Pulmonary effects of leukotrienes.

Dahlén Se · PubMed · 1983 · 36 citations

Veterinary Medicine, Pharmacology, Pharmacotherapy +12