Science · 1970 · 56 citations · 6 references
Natural ResourcesMarine BiologyFish PhysiologyFisheries BiologyMarine PhysiologyCystic FibrosisGill DiseaseCiliary BeatingCiliary BiologyCystic Fibrosis GeneticsEnzyme Inhibitors From Marine SourcesImmunoglobulin G ResponsesMarine Enzyme InhibitorsMolecular Weight Determination
The inhibitor to oyster ciliary activity was isolated from serumof cystic fibrosis patients and heterozygotes. The inhibitinig protein fraction wast a cation as judged by electrophoresis; it had a molecuer weight of 125,000 to 200,000 as judged by gel filtration; antd oil diethylaminoethyl-cellulose chromatography it eluted with the immunoglobulin G fraction. The analogous fraction in normal individuals did not inhibit oyster cillary activity.
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Abnormal Serum Factor in Patients with Cystic Fibrosis of the Pancreas
Alexander Spock, H. M. C. Heick, Hertha R. Cress et al. · Pediatric Research · 1967 · 231 citations