Enhanced in vivo monooxygenase activities of mammalian P450s in engineered yeast cells producing high levels of NADPH-P450 reductase and human cytochrome b5

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 3.5K citations · Full text

Life Sciences, Biochemistry, Chemistry +8

A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

Jef D. Boeke, Francois La Croute, Gerald R. Fink · Molecular and General Genetics MGG · 1984 · 2.4K citations

Life Sciences, Genetics, Molecular Biology +8

A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site.

L Guarente, R. Rogers Yocum, Paula Gifford · Proceedings of the National Academy of Sciences · 1982 · 574 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli.

Henry Barnes, Michael P. Arlotto, Michael R. Waterman · Proceedings of the National Academy of Sciences · 1991 · 563 citations

Life Sciences, Biochemistry, Molecular Biology +17

Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s

David J. Waxman, D P Lapenson, Toshifumi Aoyama et al. · Archives of Biochemistry and Biophysics · 1991 · 324 citations

Life Sciences, Biochemistry, Molecular Biology +14