Concepedia

The Human Rho-GEF Trio and Its Target GTPase RhoG Are Involved in the NGF Pathway, Leading to Neurite Outgrowth

Soline Estrach, Susanne Schmidt, Sylvie Diriong, Aubin Penna, Anne Blangy, Philippe Fort, Anne Debant

Current Biology · 2002 · 151 citations · 16 references

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16

Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

Kees Jalink, E.J. van Corven, Trudi Hengeveld et al. · The Journal of Cell Biology · 1994 · 610 citations · Full text

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Rho Family GTPases and Neuronal Growth Cone Remodelling: Relationship between Increased Complexity Induced by Cdc42Hs, Rac1, and Acetylcholine and Collapse Induced by RhoA and Lysophosphatidic Acid

Robert Kozma, Shula Sarner, Sohail Ahmed et al. · Molecular and Cellular Biology · 1997 · 601 citations · Full text

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The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains.

Anne Debant, Carles Serra‐Pages, Katja Seipel et al. · Proceedings of the National Academy of Sciences · 1996 · 465 citations

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UNC-73 Activates the Rac GTPase and Is Required for Cell and Growth Cone Migrations in C. elegans

Robert Steven, Terrance J. Kubiseski, Hong Zheng et al. · Cell · 1998 · 319 citations · Full text

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Trio Combines with Dock to Regulate Pak Activity during Photoreceptor Axon Pathfinding in Drosophila

Timothy P. Newsome, Susanne Schmidt, Georg Dietzl et al. · Cell · 2000 · 318 citations · Full text

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