Analysis of oligomeric stability of insulin analogs using hydrogen/deuterium exchange mass spectrometry

Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation

Zhongqi Zhang, David L. Smith · Protein Science · 1993 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Pharmacokinetics and pharmacodynamics of subcutaneous injection of long-acting human insulin analog glargine, NPH insulin, and ultralente human insulin and continuous subcutaneous infusion of insulin lispro.

Mauro Lepore, Simone Pampanelli, Carmine G. Fanelli et al. · Diabetes · 2000 · 820 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

The Mechanism of Protraction of Insulin Detemir, a Long-Acting, Acylated Analog of Human Insulin

Svend Havelund, Anne Plum, Ulla Ribel et al. · Pharmaceutical Research · 2004 · 431 citations

Life Sciences, Biochemistry, Endocrinology +16

Characterization of the Oligomeric States of Insulin in Self-Assembly and Amyloid Fibril Formation by Mass Spectrometry

Ewan J. Nettleton, Paula Tito, Margaret Sunde et al. · Biophysical Journal · 2000 · 288 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Insulin aspart (B28 asp-insulin): a fast-acting analog of human insulin: absorption kinetics and action profile compared with regular human insulin in healthy nondiabetic subjects.

Sunder Mudaliar, Fedon Alexander Lindberg, M. Joyce et al. · Diabetes Care · 1999 · 272 citations

Medicine, Pharmacokinetics, Pharmacology +14