Vitiligo and Multiple Glandular Insufficiencies

Abstract

Seven patients had vitiligo associated with pluriglandular insufficiency. There may be a common autoimmune pathogenesis. Vitiligo may be a readily identifiable and early external manifestation, pointing to a possible multiple glandular insufficiency syndrome. Because of the serious nature of the associated glandular deficiencies, and since they appear sequentially, yearly examinations for the associated conditions are probably indicated in the propositus and on blood relatives.