Annals of Internal Medicine · 1960 · 60 citations · 15 references
MedicineNephrologyPathologyHematopathologyRenal PathologyRenal PathophysiologyMultiple MyelomaRenal DiseaseRenal ImmunopathologyRenal NeoplasmsRenal Tubular DisordersKidney Biopsy FindingsKidney DiseasesMyeloma PathogenesisRenal Immune Complex DepositionRenal Lesion DescriptionRenal Tubular AtrophyRenal Tubular Dysfunction
Article1 January 1960RENAL PATTERNS IN MYELOMAL. M. SANCHEZ, M.D., C. A. DOMZ, M.D., F.A.C.P.L. M. SANCHEZ, M.D., C. A. DOMZ, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-1-44 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Excerpt"Myeloma kidney" is a term descriptive of the pathologic changes associated with lamellated protein deposits in the renal tubules of patients with multiple myeloma. Clinical manifestations of this process heretofore have been only sketchily delineated. Moreover, two other pathogenetic mechanisms, paramyloidosis and secondary hypogammaglobulinemia, may give rise to significant renal abnormalities in myeloma patients. Review of experience with 30 myeloma patients at this hospital disclosed that renal disease is a common guise under which myeloma may masquerade and elude diagnosis. The purpose of this report is to illustrate and classify the diverse renal syndromes which may be encountered in plasma...Bibliography1. SnapperTurnerMoscovitz ILBHL: Multiple myeloma, 1953, Grune & Stratton, Inc., New York. Google Scholar2. Oliver J: New directions in renal morphology; a method, its results, and its future, Harvey Lectures 40: 102, 1944-45. Google Scholar3. KarkPiraniPollakMuehrckeBlainey RMCLVEREJD:. The nephrotic syndrome in adults: a common disorder with many causes, Ann. Int. Med. 49: 751, 1958. LinkGoogle Scholar4. RoussakOleesky NJS: Water-losing nephritis; a syndrome simulating diabetes insipidus, Quart. J. Med. 23: 147, 1954. MedlineGoogle Scholar5. EngleWallis RLLA: Multiple myeloma and the adult Fanconi syndrome. I. Report of a case with crystal-like deposits in the tumor cells and in the epithelial cells of the kidney, Am. J. Med. 22: 5, 1957. CrossrefMedlineGoogle Scholar6. ElkintonDanowski JRTS: The body fluids, 1955, The Williams and Wilkins Co., Baltimore, p. 321. Google Scholar7. Wagener HP: Retinopathy in diabetes mellitus, Proc. Am. Diabetes A. 5: 201, 1945. Google Scholar8. PerillieConn PEHO: Acute renal failure after intravenous pyelogram in plasma cell myeloma, J. A. M. A. 167: 2186, 1958. CrossrefMedlineGoogle Scholar9. : Multiple myeloma, current clinical and chemical concepts, Am. J. Med. 23: 283, 1957. MedlineGoogle Scholar10. GlenchurZinnemanHall HHHWH: A review of fifty-one cases of multiple myeloma, Arch. Int. Med. 103: 173, 1959. CrossrefGoogle Scholar11. BayrdHech EDFJ: Multiple myeloma, review of eighty-three proved cases, J. A. M. A. 133: 147, 1947. CrossrefMedlineGoogle Scholar12. Brownell EG: Multiple myeloma, review of sixty-one proved cases, Arch. Int. Med. 95: 699, 1955. CrossrefGoogle Scholar13. CarsonAckermanMaltby CPLVJD: Plasma cell myeloma. A clinical, pathologic and roentgenologic review of ninety cases, Am. J. Clin. Path. 25: 849, 1955. CrossrefMedlineGoogle Scholar14. KennyMaloney JJWC: Multiple myeloma, diagnosis and management in a series of 57 cases, Ann. Int. Med. 46: 1079, 1957. LinkGoogle Scholar15. Mallory TB: Case reports, New England J. Med. 221: 986, 1939. Google Scholar16. GreenwaldBronfinAuerbach HPGJO: Needle biopsy of the kidney. A report of five cases of multiple myeloma, Am. J. Med. 15: 198, 1953. CrossrefMedlineGoogle Scholar17. HarnagelKleinbergKahlstromRhudy EEISCFV: Multiple myeloma, California Med. 87: 237, 1957. MedlineGoogle Scholar18. Armstrong JB: A study of renal function in patients with multiple myeloma, Am. J. M. Sc. 219: 488, 1950. CrossrefMedlineGoogle Scholar19. GoldmanAdamsLuchsinger RWSEB: Renal function in multiple myeloma, J. Lab. and Clin. Med. 40: 519, 1952. MedlineGoogle Scholar20. GeschichterCopeland CFMM: Tumors of bone, 1949, J. B. Lippincott Co., Philadelphia, p. 445. Google Scholar21. DomzDickson CADR: The agammaglobulinemias: relations and implications, Am. J. Med. 23: 917, 1957. CrossrefMedlineGoogle Scholar22. Putnam F: Aberrations of protein metabolism in multiple myeloma, Physiol. Rev. 37: 512, 1957. CrossrefMedlineGoogle Scholar23. Putnam FW: The heterogeneity of serum globulins, J. Cell. and Comp. Physiol. 47 (Suppl. 1): 17, 1956. CrossrefGoogle Scholar24. PutnamMiyake FWA: On the nonidentity of Bence Jones proteins, Science 120: 848, 1954. CrossrefMedlineGoogle Scholar25. EffersoeTedstrom PB: Detection of myeloma protein in urine by a new quick method, J. Lab. and Clin. Med. 50: 134, 1957. MedlineGoogle Scholar26. PotterFaheyPilgrim MJLHI: Abnormal serum protein and bone destruction in transmissible mouse plasma cell neoplasm (multiple myeloma), Proc. Soc. Exper. Biol. and Med. 94: 327, 1957. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Santa Barbara, California*Received for publication April 21, 1959.Read in part at the Southern California Regional Meeting of The American College of Physicians, Palm Springs, February 7-8, 1959.From the Santa Barbara Cottage Hospital and The Sansum Medical Clinic, Santa Barbara, California.Requests for reprints should be addressed to C. A. Domz, M.D., The Sansum Medical Clinic, 317 West Pueblo Street, Santa Barbara, California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRandall-Type Monoclonal Immunoglobulin Deposition Disease: New Insights into the Pathogenesis, Diagnosis and ManagementMaladie de dépôts d'immunoglobulines monoclonales de type Randall : du diagnostic au traitementLight Chain Deposition Disease: A Model of Glomerulosclerosis Defined at the Molecular LevelNodular Glomerulosclerosis with Deposition of Monoclonal Immunoglobulin Heavy Chains Lacking C H 1Ultrastructural Immunolabeling: A Unique Diagnostic Tool in Monoclonal Light Chain-Related Renal DiseasesSouthwestern Internal Medicine Conference: Renal Failure Following Radiologic ProceduresMultiple Myeloma and Renal FunctionMonoclonal Immunoglobulin Deposition Disease: Immunopathologic Aspects of Renal InvolvementLight-chain nephropathyRenal Disease in the Geriatric PatientLiteraturverzeichnisLight chain nephropathyThe Kidney in Systemic DiseaseTubular proteinuria in myelomaGamma a Myeloma with Hyperviscosity and Obstructive UropathyHyperkalemia complicating splenic irradiation of chronic lymphocytic leukemiaDie PlasmocytomniereEFFECTS OF NEOPLASMS ON RENAL ELECTROLYTE FUNCTIONParaproteinämische HämoblastosenCharacterization of Proteinuria in Patients with Monoclonal Gammopathies through Sodium Dodecyl Sulphate—Polyacrylamide Gel ElectrophoresisMultiple Myeloma of IgA Type in a DogRoentgen diagnosis of the kidney and the ureterMyeloma nephropathyChronic Hemodialysis in MyelomatosisSTEPHEN H. LEECH, M.B., HERBERT F. POLESKY, M.D., FRED L. SHAPIRO, M.D.Structure and function of the kidney in multiple myelomaRenal complications in multiple myeloma: Pathophysiology and some aspects of clinical managementLysozymuria and renal tubular dysfunction in monocytic and myelomonocytic leukemiaPLASMA CELL NEPHROPATHY WITH RENAL TUBULAR ACIDOSISImmunofluorescent studies of the myeloma kidney with special reference to light chain diseaseNiere bei Tumoren, Blutkrankheiten und ParaproteinämienThe Gamma GlobulinsUltrastructure of the kidney in a patient with multiple myelomaBence Jones proteinemiaMacroglobulinemic nephropathyMetabolic balance study of a patient with multiple myeloma treated with dexamethasoneTHE ASSOCIATION OF RENAL TUBULAR ACIDOSIS WITH HYPERGLOBULINAEMIC PURPURAExfoliated `myeloma cells' in the urine of a case of multiple myelomatosisRENAL AMYLOIDOSIS*ROBERT D. LINDEMAN, M.D., ROBERT L. SCHEER, M.D., LAWRENCE G. RAISZ, M.D. 1 January 1960Volume 52, Issue 1Page: 44-54KeywordsAmyloidosisAnemiaDiarrheaMultiple myelomaMyelomaProteinsPyelonephritisRenal diseasesSpineStaphylococcus aureus Issue Published: 1 January 1960 PDF downloadLoading ...
15
Edwin D. Bayrd · Journal of the American Medical Association · 1947 · 136 citations
Medicine, Hematology, Oncology +11
THE NEPHROTIC SYNDROME IN ADULTS: A COMMON DISORDER WITH MANY CAUSES
RobertM. Kark, Conrad L. Pirani, Victor E. Pollak et al. · Annals of Internal Medicine · 1958 · 132 citations
Multiple myeloma and the adult Fanconi syndrome
Ralph L. Engle, Lila A. Wallis · The American Journal of Medicine · 1957 · 127 citations
Medicine, Hematology, Oncology +14