A fluorescent probe for rapid detection of hydrogen sulfide in blood plasma and brain tissues in mice

Yong Qian, Ling Zhang, Shuting Ding, Xin Deng, Chuan He, Xi Zheng, Hai-Liang Zhu, Jing Zhao

Chemical Science · 2012 · 190 citations · 21 references

Concepts

Abstract

We describe the design, synthesis and application of a sensitive, selective, and fast fluorescent probe for H2S detection. A linear relationship between emission intensity and sulfide concentration was observed in biological bovine plasma systems. With this probe, we were able to estimate the sulfide concentration in mouse blood plasma and brain tissues.

References

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