Concepedia

Significance of reagent addition sequence in the amidation of carboxylic acids mediated by PPh<sub>3</sub> and I<sub>2</sub>

Sirilak Wangngae, Chuthamat Duangkamol, Mookda Pattarawarapan, Wong Phakhodee

RSC Advances · 2015 · 35 citations · 42 references

DOI

Concepts

Abstract

The outcome of the amidation reaction mediated by PPh<sub>3</sub>–I<sub>2</sub> was found to be highly dependent on the addition sequence of the reagents.

References

42

A “Traceless” Staudinger Ligation for the Chemoselective Synthesis of Amide Bonds

Eliana Saxon, Joshua I. Armstrong, Carolyn R. Bertozzi · Organic Letters · 2000 · 658 citations

, , +10

Staudinger Ligation:  A Peptide from a Thioester and Azide

Bradley L. Nilsson, Laura L. Kiessling, Ronald T. Raines · Organic Letters · 2000 · 515 citations

, , +8

Controlled and Chemoselective Reduction of Secondary Amides

Guillaume Pelletier, William S. Bechara, André B. Charette · Journal of the American Chemical Society · 2010 · 283 citations

, , +12

Enzyme-Like Chemoselective Acylation of Alcohols in the Presence of Amines Catalyzed by a Tetranuclear Zinc Cluster

Takashi Ohshima, Takanori Iwasaki, Yusuke Maegawa et al. · Journal of the American Chemical Society · 2008 · 181 citations

, , +16

Organic Ligand‐Free Alkylation of Amines, Carboxamides, Sulfonamides, and Ketones by Using Alcohols Catalyzed by Heterogeneous Ag/Mo Oxides

Xinjiang Cui, Yan Zhang, Feng Shi et al. · Chemistry - A European Journal · 2010 · 177 citations

, , +17