Circulation Research · 1955 · 15 citations · 0 references
MedicineCardiologyPharmacologyCardiovascular PharmacotherapyElectrophysiologyGeneral PharmacologyAntiarrhythmic TherapyArrhythmia PharmacotherapyAtrial FibrillationCalcium SignalingCardiac ArrhythmiasIntracellular Calcium SignalingAntiarrhythmic Drug EffectsAntiarrhythmic MedicationsAntiarrhythmic PharmacologyDrug-induced ArrhythmiasQuinidine Therapy
The effect of quinidine, procaine amide and five new antiarrhythmic compounds on calcium-induced arrhythmias in the rat are described. When the compounds prevented fibrillation, the other actions of calcium on cardiac rhythm were revealed.