International Journal of Bioinformatics Research and Applications · 2013 · 13 citations · 40 references
Life SciencesPlant BiologyPlant SciencesGene ExpressionPlant GeneticsPlant Molecular BiologyAbiotic Stress ToleranceDrought ToleranceMicrorna BiologyMicrorna-mediated RegulationPlant Gene ExpressionPlant Small Rna BiologyDrought Stress Response GenesDrought Stress ResponsesDrought-induced Gene ExpressionDrought-inducible Gene ExpressionGene Expression Regulation Under DroughtMicrorna-mediated Stress RegulationMicrorna-mediated Stress ToleranceWater Stress Tolerance
MicroRNAs (miRNAs) are small endogenous genes regulators which regulate different processes underlying plant adaptation to abiotic stresses. To gain a deep understanding of role of miRNAs in plants, in the present study, we computationally analyzed different sorghum miRNAs in the drought-induced gene sequences. Homologous miRNA were identified using different plant miRNA databases. Using previously established genes databases, various targets of sorghum miRNAs were predicted viz: transcription factors, chaperonins, metabolic enzymes and other gene targets necessary for proper plant development. Analysis of cis-elements provides molecular evidence for the possible involvement of miRNAs in the process of abiotic stress tolerance in sorghum. Based on these results, it was suggested that miRNAs may play an important role in water stress tolerance.
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The functions of animal microRNAs
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miRBase: tools for microRNA genomics
Sam Griffiths‐Jones, Harpreet K. Saini, Stijn van Dongen et al. · Nucleic Acids Research · 2007 · 4.4K citations · Full text