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Extraction and Purification of Effective Antimicrobial Constituents of Terminalia chebula RETS. against Methicillin-Resistant Staphylococcus aureus.
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1997
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Terminalia Chebula RetsAntimicrobial ChemotherapyEtoh ExtractMedicinal ChemistryPhytochemicalAntimicrobial ResistanceAntimicrobial Drug DiscoveryMethicillin-resistant Staphylococcus AureusBioassay-guided IsolationGallic AcidTerminalia Chebula RetzAntibacterial AgentAntimicrobial CompoundPharmacologyClinical MicrobiologyAntibioticsEffective Antimicrobial ConstituentsMicrobiologyPhytochemistryMedicine
Examination of the EtOH extract of the fruiting bodies of Terminalia chebula RETZ. led to the isolation of two potent antimicrobial substances against even methicillin-resistant strains of Staphylococcus aureus. On the basis of spectroscopic evidence, the two isolates have been identified as gallic acid and its ethyl ester.