Concepedia

Claudin-1 Is a Metastasis Suppressor and Correlates with Clinical Outcome in Lung Adenocarcinoma

Yu-Chih Chao, Szu‐Hua Pan, Shuenn-Chen Yang, Sung‐Liang Yu, Ting-Fang Che, Chung‐Wu Lin, Mu-Shiun Tsai, Gee‐Chen Chang, Che-Hsiang Wu, Yi-Ying Wu,

American Journal of Respiratory and Critical Care Medicine · 2008 · 171 citations · 41 references

DOI

Abstract

CLDN1 is a cancer invasion/metastasis suppressor. CLDN1 is also a useful prognostic predictor and potential drug treatment target for patients with lung adenocarcinoma.

References

41

Revisions in the International System for Staging Lung Cancer

Clifton F. Mountain · CHEST Journal · 1997 · 4.6K citations

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Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands

Kazumasa Morita, Mikio Furuse, Kazushi Fujimoto et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations

Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer

Punita Dhawan · Journal of Clinical Investigation · 2005 · 539 citations · Full text

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Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut

Christoph Rahner, Laura L. Mitic, James M. Anderson · Gastroenterology · 2001 · 534 citations

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Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast

Scott L. Kominsky, Pedram Argani, Dorian Korz et al. · Oncogene · 2003 · 441 citations

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