Anesthesiology · 1980 · 431 citations · 0 references
MedicineAnesthesiologyPharmacologyAnesthesiaGeneral AnesthesiaPerioperative PharmacologyAnesthetic Drug PharmacologyAnesthetic PharmacologyIntraoperative Medication AdministrationPharmacokinetics In SurgeryIntraoperative PharmacokineticsKetamine PharmacologyKetamine-based AnesthesiaPostoperative Pharmacokinetics
To assess the intraoperative and postoperative effects of the optical isomers of ketamine. compared with the racemic mixture as sole anesthetics, equianesthetic doses of racemic ketamine (RK), 2 mg/kg, (+)ketamine (PK), 1 mg/kg, and (−)ketamine (MK), 3 mg/kg, were administered intravenously in a ran