Synthesis of arginine-based surfactants in highly concentrated water-in-oil emulsions

Abstract

Synthesis of the cationic surfactant Nα-lauroylarginine methyl ester hydrochloride (LAM) has been carried out using highly concentrated water-in-oil emulsions as new reaction media. The influence of reaction time, ArgOMe-dodecanoic acid molar ratio, temperature and the volume fraction of the dispersed phase on reaction yield has been studied. A new HPLC analysis procedure and a MPLC purification for LAM is described.