Publication | Open Access

Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis

BiochemistryMitochondrial FunctionMedicineApoptosisCell DeathAnti-cancer AgentPharmacologyTrail-induced ApoptosisCancer ResearchOxidative Stress